The effect of sex and age on cortical grey and white matter volumes of frontal lobe

Grey matter (GM) of the frontal lobe carries out its complex function such as muscle control, speech, decision making, and self-control; while white (WM) is a major contributor to human brain enlargement higher structural connectivity. This study was conducted assess effect sex age on grey volumes (GMV WMV) gyri in healthy young adult Sudanese. The present included 139 Sudanese subjects (80 males 59 females). Participant’s ages were ranging between 20-40 years. T1-weighted MR images with thickness 1mm obtained. analyzed using automatic segmentation software (BrainSuite). GMV WMV estimated output data process software. Males had greater lobes (251.18±31.80cm3 143.48±22.92cm3, respectively) most (P<0.05). Change has been reported lobes, superior gyrus, pars orbitalis, orbitofrontal, cingulate gyrus WM found cingulate, precentral, paracentral Sex prominent gyri, thus differences individuals. Age these findings confirm continuation maturation until fourth decade. Assessing GM importance distinguish normal from diseased.